"...has God said...?"
This spirit of questioning was uttered from a heart of rejection and led to acts of rebellion. Long before he possessed the form of the serpent there in the garden, Satan had led a third of the angelic host in revolt against the Lord God in His heavenly rule. His inveterate hatred has never wavered, never lost intensity of purpose: steal God's worship, and hinder His worshippers' knowledge of Him.
How? Often through casting doubt on God's character and Word by a spirit of questioning, rather than acceptance by faith. Saturating the world's system is this spirit of discontent, fueled by refusal to submit to God's sovereign rule over all. Indeed, such submission is viewed as intellectual suicide, and disdained.
Yet for those who take God seriously, James 4:7,8a, are precious: "Submit therefore to God. Resist the devil and he will flee from you. Draw near to God and He will draw near to you."